Shane Crotty Selected Research

Smallpox Vaccine (Vaccine, Smallpox)

8/2012	Structural and biochemical characterization of the vaccinia virus envelope protein D8 and its recognition by the antibody LA5.
1/2012	Protection of rabbits and immunodeficient mice against lethal poxvirus infections by human monoclonal antibodies.
1/2011	Protective murine and human monoclonal antibodies against eczema vaccinatum.
10/2007	Monkeypox-induced immunity and failure of childhood smallpox vaccination to provide complete protection.
5/2007	Proteome-wide analysis of the serological response to vaccinia and smallpox.
6/2006	Immunity and immunological memory following smallpox vaccination.
9/2005	Vaccinia virus H3L envelope protein is a major target of neutralizing antibodies in humans and elicits protection against lethal challenge in mice.

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Shane Crotty Research Topics

Disease

33	Infections 08/2022 - 02/2002
17	COVID-19 03/2022 - 01/2020
12	Virus Diseases (Viral Diseases) 01/2021 - 02/2002
10	Vaccinia 01/2017 - 01/2005
9	Communicable Diseases (Infectious Diseases) 01/2022 - 03/2004
9	Smallpox (Variola) 05/2016 - 11/2003
6	Neoplasms (Cancer) 01/2019 - 02/2010
2	Cytokine Release Syndrome 06/2021 - 04/2021
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2021 - 10/2014
2	Tuberculosis (Tuberculoses) 01/2020 - 01/2016
2	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 01/2016
2	Atherosclerosis 01/2019 - 01/2018
2	Tetanus 01/2018 - 01/2017
2	Whooping Cough (Pertussis) 01/2018 - 06/2016
2	Inflammation (Inflammations) 10/2016 - 12/2008
2	Dengue (Dengue Fever) 01/2016 - 08/2015
2	Mpox (monkeypox) 09/2015 - 10/2007
2	Kaposi Varicelliform Eruption (Eczema Herpeticum) 01/2011 - 06/2009
2	Persistent Infection 01/2008 - 10/2006
2	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2007 - 01/2006
2	Respiratory Syncytial Virus Infections 11/2002 - 02/2002
2	Lassa Fever (Fever, Lassa) 11/2002 - 02/2002
1	Breakthrough Infections 01/2022
1	Lung Injury 01/2021
1	Reinfection 01/2021
1	Human Influenza (Influenza) 01/2020
1	Hypersensitivity (Allergy) 01/2019
1	Tonsillitis 01/2019
1	Ovarian Neoplasms (Ovarian Cancer) 01/2018
1	Melanoma (Melanoma, Malignant) 12/2017
1	Yellow Fever 01/2017
1	Bacterial Infections (Bacterial Infection) 01/2017
1	HIV Infections (HIV Infection) 01/2016
1	Neoplasm Metastasis (Metastasis) 10/2015
1	Lymphoma (Lymphomas) 10/2015
1	Ectromelia (Phocomelia) 09/2015
1	Severe Dengue 08/2015
1	Listeriosis (Listeria Infection) 02/2015
1	Disease Progression 07/2014
1	Hyperplasia 07/2014
1	Poxviridae Infections 01/2012
1	Aseptic Meningitis 05/2010
1	Lymphocytic Choriomeningitis 05/2010
1	Fever (Fevers) 05/2010
1	Arenaviridae Infections 05/2010
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2010
1	Atopic Dermatitis (Atopic Eczema) 06/2009
1	Dermatitis 06/2009

Drug/Important Bio-Agent (IBA)

38	VaccinesIBA 08/2022 - 03/2004
17	AntigensIBA 01/2021 - 10/2004
12	EpitopesIBA 01/2022 - 07/2007
12	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2005
7	COVID-19 VaccinesIBA 03/2022 - 01/2021
7	Immunoglobulin G (IgG)IBA 01/2017 - 01/2003
7	Smallpox Vaccine (Vaccine, Smallpox)FDA Link 08/2012 - 09/2005
6	Monoclonal AntibodiesIBA 01/2022 - 01/2010
6	AntibodiesIBA 01/2022 - 12/2009
6	Transcription Factors (Transcription Factor)IBA 08/2021 - 10/2014
4	Neutralizing AntibodiesIBA 01/2021 - 10/2006
4	CytokinesIBA 01/2017 - 07/2007
4	Antiviral Agents (Antivirals)IBA 12/2015 - 02/2002
4	Signaling Lymphocytic Activation Molecule Associated ProteinIBA 01/2007 - 01/2006
3	Broadly Neutralizing AntibodiesIBA 01/2021 - 01/2016
3	Immunoglobulins (Immunoglobulin)IBA 01/2012 - 10/2004
3	ProteomeIBA 05/2007 - 01/2005
2	Interleukin-15 (Interleukin 15)IBA 06/2021 - 04/2021
2	BNT162 VaccineIBA 03/2021 - 01/2021
2	ChromatinIBA 01/2021 - 01/2017
2	Peptides (Polypeptides)IBA 01/2020 - 07/2007
2	Viral VaccinesIBA 01/2018 - 01/2017
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 10/2007
2	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 01/2018 - 01/2017
2	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 08/2015 - 05/2010
2	Interleukin-6 (Interleukin 6)IBA 04/2013 - 03/2011
2	Immunoglobulin M (IgM)IBA 12/2009 - 10/2007
1	N-(2-cyanoethylene)urea (BA 1)IBA 03/2022
1	N-methyl-valyl-amiclenomycin (BA 2)IBA 03/2022
1	mRNA VaccinesIBA 01/2022
1	InterferonsIBA 10/2021
1	NucleotidesIBA 08/2021
1	Messenger RNA (mRNA)IBA 03/2021
1	Angiotensin-Converting Enzyme 2IBA 01/2021
1	AerosolsIBA 01/2021
1	HDL LipoproteinsIBA 01/2018
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2018
1	LuciferasesIBA 01/2017
1	Signaling Lymphocytic Activation Molecule FamilyIBA 03/2016
1	Pertussis VaccineIBA 01/2016
1	HLA-A Antigens (HLA-A)IBA 01/2016
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 02/2015
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 02/2015
1	Cell Surface ReceptorsIBA 02/2015
1	MicroRNAs (MicroRNA)IBA 08/2014
1	interleukin-21 (interleukin 21)IBA 07/2014
1	ElementsIBA 07/2014
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 07/2014
1	Combined VaccinesIBA 05/2010

Therapy/Procedure

5	Therapeutics 12/2017 - 01/2010
1	Tonsillectomy 01/2019
1	Cell- and Tissue-Based Therapy (Cell Therapy) 12/2017